AutoKarnet

Mercedes Classe S W221 (2005 to 2013)

The Mercedes Classe S W221 was built from 2005 to 2013. Choose your engine: each page gives the engine, the output and what to know for servicing.

Choose an engine

Engines

S 350: M272 3.5 V6, 272 hp (200 kW), 2005 to 2010 S 350: M276 3.5 V6, 306 hp (225 kW), 2010 to 2013 S 500: M273 5.5 V8, 388 hp (285 kW), 2005 to 2010 S 500: M278 4.7 V8, 435 hp (320 kW), 2010 to 2013 S 400 Hybrid: M272 3.5 V6, 299 hp (220 kW), 2009 to 2013 S 320 CDI: OM642 3.0 V6 CDI, 235 hp (173 kW), 2005 to 2009 S 350 BlueTEC: OM642 3.0 V6 CDI, 258 hp (190 kW), 2010 to 2013

Maintenance

ASSYST indicator: it alternates between Service A (oil change and checks) and Service B (more extensive, with filters and brake fluid). On recent European models, expect about 25,000 km or 1 year between services; older cars with flexible ASSYST could go up to 2 years. MB 229.5 / 229.51 / 229.52 approved oil depending on the engine. Brake fluid every 2 years.