Service A / Service B
About 25,000 km or 1 year (ASSYST)
25 000 km
12 months
Oil and filter at each service; Service B adds filters and wider checks. The ASSYST indicator prevails.
Source [1]W221 · 2005–2010
The Mercedes Classe S S 500 of the W221 generation uses the M273 5.5 V8 petrol engine with 388 hp.
Figures apply to the cited configuration and market; equipment and transmissions may vary by production date.
Specification source : [1] AutoKarnet
388 hp (285 kW), rear-wheel drive, 7-speed automatic. Built from 2005 to 2010.
AutoKarnet advice
It sits between the S 350 (306 hp) and the S 500 (435 hp). The M273 5.5 V8 engine is also fitted to: Mercedes Classe E (W211), Mercedes GLE / ML (ML W164), Mercedes Classe G (W463), Mercedes SL (R230).
AutoKarnet advice
About 25,000 km or 1 year (ASSYST)
25 000 km
12 months
Oil and filter at each service; Service B adds filters and wider checks. The ASSYST indicator prevails.
Source [1]Every 24 months
24 months
Time-based replacement, whatever the mileage.
Source [1]The M273 5.5 V8 petrol engine (5 461 cc), 388 hp (285 kW).
AutoKarnet advice
A MB 229.5 / 229.51 / 229.52-approved oil suited to the M273 5.5 V8 engine.
AutoKarnet advice
AutoKarnet · FR · Europe · Synthèse éditoriale AutoKarnet · Accessed 09/10/2026